Epithelioid sarcoma differential diagnosis

Revision as of 04:23, 21 September 2019 by Aditya Ganti (talk | contribs) (Differentiating Epithelioid sarcoma from other Diseases)
Jump to: navigation, search
Home logo1.png

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ammu Susheela, M.D. [2]


Epithelioid sarcoma must be differentiated from synovial sarcoma, wart, ganglion cysts, rhabdomyosarcoma, and clear cell sarcoma.

Differentiating Epithelioid sarcoma from other Diseases

Keratin CD34 Cytoplasm In-sutu Kerataniztion Location Age group H/O of epithelial injury CA125 CK5/6 GCDFP15, S100, actin Necrosis Calcification Hemangiopericytomatous vessels
Epitheloid Sarcoma Positive Positive Sharply defined Negative Hand and wrist Under 40 years No Positive Rare, Local Negative Extensive Infrequent Negative
Palisaded Necrotic Granuloma Neagtive Negative Indistinct Uncommon
Squamous Carcinoma Negative Positive >40 Positive Negative in cutaneous SCC

Positive everywhere

Sweat Gland Carcinoma Negative Positive
Monophasic Synovial Sarcoma Negative Negative Focal Frequent Positive
Melanoma Negative Negative Negative Positive
Epithelioid Hemangioendothelioma Negative Uncommon on extremities
Sclerosing Epithelioid Fibrosarcoma Negative Cords of cells in hylainzed stroma
Ischemic Fasciitis Negative Basophilic or amphophilic


  1. Epithelioid sarcoma. Sarcomahelp (2016). http://sarcomahelp.org/epithelioid-sarcoma.html Accessed on February 8, 2016