Glomus tumor history and symptoms

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Soujanya Thummathati, MBBS [2]

Overview

A detailed history from the patient may be helpful. A positive history of trauma may be present. A positive family history may be present in patients with multiple glomus tumors (autosomal dominant).Symptoms of glomus tumor include hypersensitivity to cold and paroxysmal pain at a well defined site.

History

  • A detailed history from the patient may be helpful. A positive history of trauma may be present.[1]
    • There is a delay in diagnosis of the lesions (sometimes up to 15 years) that was apparent both in several cases described in the literature.[2][3]
  • A positive family history may be present in patients with multiple glomus tumors (autosomal dominant).[1]

Symptoms

  • Symptoms of solitary glomus tumor include:[4][5]
    • Pain
      • Paroxysmal
      • Cold sensitivity
        • Reproduced when the lesion is placed in cold water
      • May worsen at night
      • Extreme point tenderness in the region of the tumor
      • Disappears when a tourniquet is applied
      • Subungual glomus tumors are particularly painful
    • Multiple glomus tumors are usually painless.

References

  1. 1.0 1.1 Blanchard AJ (1941). "The Pathology of Glomus Tumours". Can Med Assoc J. 44 (4): 357–60. PMC 1827043. PMID 20322052.
  2. Pater TJ, Marks RM (2004). "Glomus tumor of the hallux: case presentation and review of the literature". Foot Ankle Int. 25 (6): 434–7. doi:10.1177/107110070402500614. PMID 15215032.
  3. Tomak Y, Akcay I, Dabak N, Eroglu L (2003). "Subungual glomus tumours of the hand: diagnosis and treatment of 14 cases". Scand J Plast Reconstr Surg Hand Surg. 37 (2): 121–4. PMID 12755514.
  4. Brouillard P, Ghassibé M, Penington A, Boon LM, Dompmartin A, Temple IK; et al. (2005). "Four common glomulin mutations cause two thirds of glomuvenous malformations ("familial glomangiomas"): evidence for a founder effect". J Med Genet. 42 (2): e13. doi:10.1136/jmg.2004.024174. PMC 1735996. PMID 15689436.
  5. Samaniego E, Crespo A, Sanz A (2009). "[Key diagnostic features and treatment of subungual glomus tumor]". Actas Dermosifiliogr. 100 (10): 875–82. PMID 20038364.

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